Total 13 results found.
Tag: 2008 Ordering
Marucci G, Finaurini S, Buccioni M, Lammi C, Kandhavelu M, Volpini R, Ricciutelli M, Angeli P, Commandeur JN, Cristalli G. [2008]: In vitro metabolism studies of new adenosine A 2A receptor antagonists. Drug Metab Lett. 2(4): 301-7. PubMed
Appiah-Opong R., de Esch I., Commandeur J.N., Andarini M., Vermeulen N.P. Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues. Eur. J. Med. Chem. 43 (2008) pp: 1621-1631. Pubmed
Appiah-Opong R., Commandeur J.N., Axson C., Vermeulen N.P. Interactions between cytochromes P450, glutathione S-transferases and Ghanaian medicinal plants. Food Chem Toxicol. 46 (2008) pp: 3598-3603. Pubmed
Bonifacio A., Millo D., Keizers P.H., Boegschoten R., Commandeur J.N., Vermeulen N.P., Gooijer C., van der Zwan G. Active-site structure, binding and redox activity of the heme-thiolate enzyme CYP2D6 immobilized on coated Ag electrodes: a surface-enhanced resonance Raman scattering study. J. Biol. Inorg. Chem. 13 (2008) pp: 85-96. Pubmed
Damsten M.C., de Vlieger J.S., Niessen W.M., Irth H., Vermeulen N.P., Commandeur J.N. Trimethoprim: Novel Reactive Intermediates and Bioactivation Pathways by Cytochrome P450s. Chem. Res. Toxicol. 21 (2008) pp: 2181-2187. Pubmed
Damsten M.C., van Vugt-Lussenburg B.M., Zeldenthuis T., de Vlieger J.S., Commandeur J.N., Vermeulen N.P. Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites. Chem. Biol. Interact. 10; 171 (2008) pp: 96-107. Pubmed
Hritz J., Oostenbrink, C. Hamiltonian replica exchange molecular dynamics using soft-core interactions. J. Chem. Phys. 128 (2008) pp: 144121. Pubmed
Hritz J., de Ruiter A., Oostenbrink C. Impact of plasticity and flexibility on docking results for Cytochrome P450 2D6: a combined approach of molecular dynamics and ligand docking. J. Med. Chem. 51 (2008) pp: 7469-7477. Pubmed
Jenkins R.E., Kitteringham N.R., Goldring C.E., Dowdall S.M., Hamlett J., Lane C.S., Boerma J.S., Vermeulen N.P., Park B.K. Glutathione-S-transferase pi as a model protein for the characterisation of chemically reactive metabolites. Proteomics 8 (2008) pp: 301-315. Pubmed
Kool J., van Marle A., Hulscher S., Selman M., van Iperen D.J., van Altena K., Gillard M., Bakker R.A., Irth H., Leurs R., Vermeulen N.P. A flow-through fluorescence polarization detection system for measuring GPCR-mediated modulation of cAMP production. J. Biomol. Screening. 12 (2008) pp: 1074-1083. Pubmed
Reinen J., Kool J., Vermeulen N.P. Reversed-phase liquid chromatography coupled on-line to estrogen receptor bioaffinity detection based on fluorescence polarization. Anal. Bioanal. Chem. 390 (2008) pp: 1987-1998. Pubmed
Stjernschantz E., van Vugt-Lussenburg B.M., Bonifacio A., de Beer S.B., van der Zwan G., Gooijer C., Commandeur J.N., Vermeulen N.P., Oostenbrink C. Structural rationalization of novel drug metabolizing mutants of cytochrome P450 BM3. Proteins 71 (2008) pp: 336-352. Pubmed
Stjernschantz E., Vermeulen N.P., Oostenbrink C. Computational prediction of drug binding and rationalisation of selectivity towards Cytochromes P450. Expert Opin. Drug Metab. Toxicol. 4 (2008) pp: 513-527. Pubmed